High-resolution phase-contrast X-ray imaging for biological soft tissue
نویسندگان
چکیده
Minimizing the distance between sample and detector achieves high spatial resolution while maintaining contrast of biological tissue.
منابع مشابه
High-throughput, high-resolution X-ray phase contrast tomographic microscopy for visualisation of soft tissue
The use of conventional absorption based X-ray microtomography can become limited for samples showing only very weak absorption contrast. However, a wide range of samples studied in biology and materials science can produce significant phase shifts of the Xray beam, and thus the use of the phase signal can provide substantially increased contrast and therefore new and otherwise inaccessible inf...
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An X-ray interferometer for high-resolution phase-contrast X-ray imaging was developed by thinning the central part of the analyzer crystal of a triple Laue-case (LLL) X-ray interferometer. The interferometer was tested at beamline 47XU at the SPring-8, and the improvement of the resolution of interference patterns was successfully observed for a plastic sphere of 1 mm diameter.
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This paper investigates the 3D microscopic structure of exvivo human cardiac muscle. Usual 3D imaging techniques such as DMRI or CT do not achieve the required resolution to visualise cardio-myocytes, therefore we employ X-ray phase contrast micro-CT, developed at the European Synchrotron Radiation Facility (ESRF). Nine tissue samples from the left ventricle and septum were prepared and imaged ...
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We demonstrate high-resolution x-ray differential interference contrast DIC in a compact soft x-ray microscope. Phase contrast imaging is enabled by the use of a diffractive optical element objective which is matched to the coherence conditions in the microscope setup. The performance of the diffractive optical element objective is evaluated in comparison with a normal zone plate by imaging of ...
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In the last decade X-ray imaging based on phase contrast greatly advanced thanks to the use of unmonochromatic synchrotron hard X-rays. The recent advances are going beyond microradiology and microtomography to reach nanometre scale. This paper reviews basic theory and selected applications to biomedical and materials sciences. The forthcoming improvements in phase contrast X-ray imaging will l...
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ژورنال
عنوان ژورنال: Scilight
سال: 2023
ISSN: ['2572-7907']
DOI: https://doi.org/10.1063/10.0017774